Methods of stimulating an immune response against prostate...

Details Methods of stimulating an immune response against prostate... Methods of stimulating an immune response against prostate...

2011-01-18

2011-01-18

Navarro, Mark (Department: 1645)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S023100, C435S235100, C435S320100, C435S975000

Reexamination Certificate

active

07871986

ABSTRACT:
The invention provides a prostate specific antigen oligo-epitope peptide (PSA-OP) that is useful as an immunogen in the prevention or treatment of prostatic cancer and in the inhibition of prostatic cancer cells and in the establishment and characterization of PSA-specific cytotoxic T-cell lines. In particular, the invention provides methods for eliciting an immune response against PSA comprising administering (i) a priming inoculation of a first recombinant virus encoding PSA-OP and (ii) one or more boosting inoculations of a second recombinant virus encoding PSA-OP, wherein the first and second recombinant viruses are from a different genus.

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