Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Reexamination Certificate
2011-07-19
2011-07-19
Rao, Deepak (Department: 1624)
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
Reexamination Certificate
active
07982037
ABSTRACT:
This invention describes novel pyrazole compounds of formula IIIa:wherein R1is T-Ring D, wherein Ring D is a 5-7 membered monocyclic ring or 8-10 membered bicyclic ring selected from aryl, heteroaryl, heterocyclyl or carbocyclyl; Rx, Ry, R2, and R2′are as described in the specification. The compounds are useful as protein kinase inhibitors, especially as inhibitors of Aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzheimer's disease.
REFERENCES:
patent: WO 00/39101 (2000-07-01), None
patent: WO 01/60816 (2001-08-01), None
Bebbington David
Charrier Jean-Damien
Golec Julian C.
Knegtel Ronald
Miller Andrew
Chung H. Joon
Rao Deepak
Vertex Pharmaceuticals Incorporated
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