Substituted 2-indolinone as PTK inhibitors containing a zinc...

Details Substituted 2-indolinone as PTK inhibitors containing a zinc... Substituted 2-indolinone as PTK inhibitors containing a zinc...

2011-04-19

2011-04-19

Saeed, Kamal A (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S465000

Reexamination Certificate

active

07928136

ABSTRACT:
The present invention relates to substituted 2-indolinone containing zinc-binding moiety based derivatives that have enhanced or unique properties as inhibitors of protein tyrosine kinase (PTK) receptors and their use in the treatment of PTK related diseases and disorders such as cancer. The said derivatives may further act as HDAC inhibitors.

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