Process and methods for the preparation of optically active...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C544S317000

Reexamination Certificate

active

07968703

ABSTRACT:
There is provided a method for resolving a compound of formula III, in the cis configuration:There is also provided a process for producing optically active compound of formula I or II:wherein: R1, R2, R3are as defined herein, the method and process involving the production, recovery and conversion of diastereomeric salts.

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patent: WO 95/29167 (1995-11-01), None
Samuel H. Wilen, “Tables of Resolving Agents and Optical Resolution”, University of Notre Dame Press, 1972, pp. 24-31 and 141-195, London.
Supplementary European Search Report of Apr. 21, 2010. European Application No. EP 05 71 4624. International Application No. PCT/CA2005/000384.
Bayley, C.R. et al.: “Resolution of Racemates by Diastereomeric Salt Formation” Chirality in Industry, Chapter 2, pp. 66-77 (1992).
Wang, W. et al. “Synthesis of Optically Active 2',3'-Dideoxy-3'-oxa-4'-thio-ribonucleoside Analogues by Transposition of a Leaving Group on Chiral Oxathiolanes via a Reductive-oxidative Process” Tetrahedron Letters, 35(27):4739-4742 (1994).

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