Hydrindane analogs having sphingosine 1-phosphate receptor...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

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C564S355000

Reexamination Certificate

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07964649

ABSTRACT:
Hydrindane analogs that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs, which, after phosphorylation, can behave as agonists at S1P receptors.

REFERENCES:
patent: 3153092 (1964-10-01), Burger
patent: 4939130 (1990-07-01), Jaeggi et al.
patent: 5405988 (1995-04-01), Klar et al.
patent: 6069251 (2000-05-01), Thurkauf et al.
patent: 6875757 (2005-04-01), Miller et al.
patent: 7060697 (2006-06-01), Marsilje et al.
patent: 7064217 (2006-06-01), Macdonald et al.
patent: 7241790 (2007-07-01), Lynch et al.
patent: 7638637 (2009-12-01), Lynch et al.
patent: 2004/0224941 (2004-11-01), Seko et al.
patent: 2005/0023386 (2005-02-01), Nishi et al.
patent: 2005/0032744 (2005-02-01), Michaelis et al.
patent: 2005/0107447 (2005-05-01), Lynch et al.
patent: 2006/0046979 (2006-03-01), Foster et al.
patent: 2006/0122181 (2006-06-01), Ikemoto et al.
patent: 2006/0135786 (2006-06-01), Saha et al.
patent: 2006/0211656 (2006-09-01), Albert et al.
patent: 2006/0223866 (2006-10-01), Evindar et al.
patent: 2007/0191313 (2007-08-01), Beard et al.
patent: 2008/0249070 (2008-10-01), Lynch et al.
patent: 2009/0042955 (2009-02-01), Lynch et al.
patent: 2009/0062238 (2009-03-01), Lynch et al.
patent: 2009/0105315 (2009-04-01), Lynch et al.
patent: 2009/0137531 (2009-05-01), Lynch et al.
patent: 2009/0253759 (2009-10-01), Lynch et al.
patent: 2009/0253761 (2009-10-01), Lynch et al.
patent: 1 056 139 (1959-04-01), None
patent: 3 544 373 (1987-06-01), None
patent: 1 553 091 (2005-07-01), None
patent: 1 602 660 (2005-12-01), None
patent: 950388 (1964-02-01), None
patent: 1994 135935 (1994-05-01), None
patent: 1994 135936 (1994-05-01), None
patent: 2002 316985 (2002-10-01), None
patent: 2004 307442 (2004-04-01), None
patent: WO 99/35259 (1999-07-01), None
patent: WO 01/60819 (2001-08-01), None
patent: WO 01/71022 (2001-09-01), None
patent: WO 02/076995 (2002-10-01), None
patent: WO 02/092068 (2002-11-01), None
patent: WO 03/059880 (2003-07-01), None
patent: WO 03/061567 (2003-07-01), None
patent: WO 2004/010987 (2004-02-01), None
patent: WO 2004/017917 (2004-03-01), None
patent: WO 2004/024673 (2004-03-01), None
patent: WO 2004/028521 (2004-04-01), None
patent: WO 2004/031129 (2004-04-01), None
patent: WO 2004/047743 (2004-06-01), None
patent: WO 2004/096752 (2004-11-01), None
patent: WO 2004/096757 (2004-11-01), None
patent: WO 2004/103279 (2004-12-01), None
patent: WO 2004/103306 (2004-12-01), None
patent: WO 2005/032465 (2005-04-01), None
patent: WO 2005/118523 (2005-12-01), None
patent: WO 2006/001463 (2006-01-01), None
patent: WO 2006/020951 (2006-02-01), None
patent: WO 2007/085451 (2007-08-01), None
patent: WO 2007/086001 (2007-08-01), None
patent: WO 2007/091396 (2007-08-01), None
patent: WO-2008064320 (2008-05-01), None
patent: WO-2008064320 (2008-05-01), None
patent: WO 2008-079382 (2008-07-01), None
patent: WO 2009/023854 (2009-02-01), None
patent: WO 2009/043013 (2009-04-01), None
patent: WO 2009/146112 (2009-12-01), None
Koo et al., Synthesis in the 5-Hydroxyindole Series. N-Acetyl-5-hydroxytryptophan and Related Compounds, 1959, Journal of Organic Chemistry, 24, 179-83.
Clemens, J J, “Synthesis of benzimidazole based analogues of sphingosine-1-phosphate: discovery of potent, subtype-selective S1P4 receptor agonists”, Bioorganic & Medicinal Chemistry Letters, Oxford, GB vol. 14, No. 19, ISSN: 0960-894x, (Oct. 4, 2004), 4903-4905.
International Search Report for PCT/US2007/085401 Apr. 30, 2008.
Bandini, M. et al.,Eur. J. Chem. 2001, 1937-1942.
Beilstein, Registry No. 6240345, 1985.
Bertus, P. et al.,Chem Commun, 2001, 1792-1793.
Brinkmann, V. et al.,Transplantation72, 2001, 764-769.
Brinkmann, V. et al.,J Biol Chem277, 2002, 21453-21457.
Burger, A. et al.,Journal of Medicine and Pharmaceutical Chemistry, vol. 4, No. 3, 1961.
Chiba, K. et al.,J Immunol160, 1998, 5037-5044.
Choi, D. et al.,J Med Chem39, 1996, 1907-1916.
Clair, T. et al.,Cancer Res63, 2003, 5446-5453.
Clemens, J. et al.,Bioorg Med Chem Lett(2003), 3401-3404.
Clemens, J. et al.,Bioorg. &Med. Chem. Lett. (2004), 4903-4906.
Clemens, J. et al.,Bioorg. &Med. Chem. Lett. (2005), 2005, 3568-3572.
Crosignani, S. et al.,Tetrahedron54, (1998), 15721-15730.
Davis, M. et al.,The J. of Bio. Chem., (2005), 9833-9841.
Dworkin, R. H. et al., Arch. Neurol., 60, 2003, p. 1524-1534.
Forrest, M. et al.,J Pharmacol Exp Ther309, 2004, 758-768.
Foss, F. et al.,Bioorganic&Medicinal Chemistry15, 2005, 4470-4474.
Foss, F. et al.,Bioorganic&Medicinal Chemistry15, 2007, 663-677.
Fujino, M. et al.,J Pharmacol Exp Ther305, 2003, 70-77.
Graler, M. H. et al.,FASEB18, 2004, 551-553.
Hale, Jeffrey J. et al.,Bioorganic&Medicinal Chemistry Letters14, 2004, 3351-3355.
Hale, J. J. et al., 2004Bioorg Med Chem Lett14, 2004, 3501-3505.
Hale, J. J. et al., (2004)Bioorg Med Chem Lett14, 3495-3499.
Hale, J. J. et al.,J Med Chem, 2004, 47, 6662-6665.
Hanessian, S. et al.,Bioorganic&Medicinal Chemistry Letters17, 2007, 491-494.
Hoshino, Y. et al., (1999)Transplant Proc31, 1224-1226.
Im, D. S. et al., (2000)J Biol Chem275, 14281-14286.
Im, D. S. et al., Biochemistry 40, 2001, 14053-14060.
Jones, L. et al., (1997)J Org Chem62, 1388-1410.
Kaiser, C. et al., XP009032189, Nov. 1962, 1243-1265.
Kawasaki, K. et al.,Tetrahedron, vol. 53, No. 18, 1997, 6337-6350.
Kharel, Y. et al.,J Bio Chem, vol. 280, No. 44, Nov. 4, 2005, 36865-36872.
Kimura, T. et al., (2003)Arterioscler Thromb Vasc Biol23, 1283-1288.
Kiuchi, M. et al.,(2000)J Med Chem43, 2946-2961.
Kon, J. et al., (1999)J Biol Chem274, 23940-23947.
Kotera et al. Chem. Abst.: Registry Record 19352-04-6, 1968.
Lee, M. J. et al., (1998)Science279, 1552-1555.
Lew, M. J. et al., “Analysis of competitive agonist-antagonist interactions by nonlinear regression”, (1995)Trends Pharmacol Sci16, 328-337.
Li, Z. et al.,Journal of Medicinal Chemistry, vol. 48, No. 20, Oct. 6, 2005, 6169-6173.
Maki, T. et al., (2002)Transplantation74, 1684-1686.
Maki, T. et al., (2005)Transplantation79, 1051-1055.
Mandala, S. et al., (2002)Science296, 346-349.
Matloubian, M. et al., (2004)Nature427, 355-360.
Sanchez, T. et al., (2003)J Biol Chem278, 47281-47290.
Sanna, M. G. et al., (2004)J Biol Chem279, 13839-13848.
Sanna, M. G. et al.,Nature Chemical Biology, vol. 2, Aug. 2006, 434-441.
Suzuki, S. et al., (1996)Transpl Immunol4, 252-255.
Van Brocklyn, J. R. et al., (1999)J Biol Chem274, 4626-4632.
Vogler, R. et al., (2005), No. 20, 2005, 6169-6173.
Xie, J. H. et al., (2003)J Immunol170, 3662-3670.
Yanagawa, Y. et al., (2000)Int J Immunopharmacol22, 597-602.
Yanagawa, Y. et al., (1999)Transplant Proc31, 1227-1229.
Yang, Z., et al., (2003)Clin Immunol107, 30-35.
Zhang, T. et al., (1997)Cancer Res57, 169-175.
Zhang, Y. H. et al.,J Neurophysiol96, 2006, 1042-1052.
Zhang, Y. H. et al.,J Physiol575.1, 2006, 101-113.
“European Application Serial. No. 07868830.6, Office Action mailed on Mar. 3, 2011”, 5 pgs.
Clemens, J. J, et al., “Synthesis of benzimidazole based analogues of sphingosine-1- phosphate: discovery of potent, subtype-selective S1P4 receptor agonists”, Bioorg Med Chem Lett., 14(19), (Oct. 4, 2004), 4903-6.

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