Dioxolenylmethyl ester prodrugs of phosphinic acid ace inhibitor

Details Dioxolenylmethyl ester prodrugs of phosphinic acid ace inhibitor Dioxolenylmethyl ester prodrugs of phosphinic acid ace inhibitor

1983-03-24

1985-11-26

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544230, 544243, 546 15, 546 22, 548413, 548112, 548113, C07F 965, A61K 31675

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active

045555796

ABSTRACT:
Angiotensin converted enzyme inhibitor activity if exhibited by compounds having the formula ##STR1## and salts thereof wherein R.sub.1 is hydrogen, aryl, or heteroaryl; R.sub.2 is hydrogen, amino, alkanoylamino, arylcarbonylamino, or heteroarylcarbonylamino;

REFERENCES:
patent: 4168267 (1979-09-01), Petrillo
patent: 4337201 (1982-06-01), Petrillo
patent: 4379146 (1983-04-01), Greenlee et al.
patent: 4427665 (1984-01-01), Karanewsky et al.
patent: 4432971 (1984-02-01), Karanewsky et al.
patent: 4448772 (1984-05-01), Karanewsky
patent: 4452791 (1984-06-01), Ryono et al.
Brietbeil et al., Trans. Ill. State Acad. Sci., 67:139-144, (1974).
Ehrenfreund et al., Tetrahedron, vol. 28, pp. 1697-1704, (1972).
Fischler, et al., Tetrahedron Letters, No. 17, pp. 1701-1704, (1972).
Sakamoto, et al., Chemical Abstracts, vol. 98, 143,458q (1982).
Christensen, et al., Chemical Abstracts, vol. 99, 10851m (1983), abstract of Eur. Pat. Appl. EP 70,013, 01/19/83.

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