Triazole-substituted arylamides as P2X 3 and P2X 2/3...

Details Triazole-substituted arylamides as P2X 3 and P2X 2/3... Triazole-substituted arylamides as P2X 3 and P2X 2/3...

2011-08-02

2011-08-02

Wilson, James O (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C544S132000, C544S238000, C544S333000, C544S405000, C546S272400

Reexamination Certificate

active

07989637

ABSTRACT:
Compounds of the formula I:or a pharmaceutically acceptable salt thereof, wherein, R1is optionally substituted triazolyl, and R2, R3, R4, R5, R6, R7and R8are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3and/or a P2X2/3receptor antagonists and methods of making the compounds.

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