Thromboxane synthetase enzyme inhibiting N-[(1H-imidazol-1-yl) a

Details Thromboxane synthetase enzyme inhibiting N-[(1H-imidazol-1-yl) a Thromboxane synthetase enzyme inhibiting N-[(1H-imidazol-1-yl) a

1984-11-19

1985-11-26

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514341, 546276, 546278, C07D40112, A61K 31455

Patent

active

045555192

ABSTRACT:
This invention concerns novel N-[(1H-imidazol-1-yl) and (1H-1,2,4-triazol-1-yl)alkyl]pyridinecarboxamides which are useful as inhibitors of thromboxane synthetase and/or as hypotensive agents in the treatment of hypertension and myocardial ischemia.

REFERENCES:
Jacob Zabicky, The Chem. of Amides, 1970, p. 117.

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