Human pinin splice variant

Details Human pinin splice variant Human pinin splice variant

1997-08-08

2000-12-19

Guzo, David

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435325, 435366, 4353201, 435 691, 435 911, 435 912, 536 231, 536 235, C12Q 168, C12N 1585, C12N 510, C07H 2104

Patent

active

061626015

ABSTRACT:
The invention provides a human pinin splice variant (PNIN) and polynucleotides which identify and encode PNIN. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of PNIN.

REFERENCES:
Duo et al., GenBank Accession No. U59479, Jul. 1996.
Finbow, M.E. et al., "Ductin--a proton pump component, a gap junction channel and a neurotramsmitter release channel", BioEssays, 17: 247-255 (1995).
Ouyang, P. and S.P. Sugrue, "Characterization of Pinin, A Novel Protein Associated with the Desmosome-Intermediate Filament Complex", J. Cell Biol., 135: 1027-1042 (1996) (GI 1684842; GI 1684843; GI 1684846; GI 1684847).
Krawczyk, W.S. and G.F. Wilgram, "Hemidesmosome and Desmosome Morphogenesis during Epidermal Wound Healing", J. Ultrastructure Res., 45: 93-101 (1973).
Plotnick, H. and A. Lupulescu, "Ultrastructural studies of xeroderma pigmentosum", J. Am. Acad. Dermatol., 9: 876-882 (1983).
Wegiel, J. and H.M. Wisniewski, "Rosenthal fibers, eosinophilic inclusions, and anchorage densities with desmosome-like structures in astrocytes in Alzheimer's disease", Acta Neuropathol., 87: 355-361 (1994).
Sepp, R. et al., "Altered patterns of cardiac intercellular junction distribution in hypertrophic cardiomyopathy", Heart, 76: 412-417 (1996).
Cooley, J.E. et al., "Hailey-Hailey Disease Keratinocytes: Normal Assembly of Cell-Cell Junctions In Virto", J. Invest. Dermatol., 107: 877-881 (1996).
Imai, Y. and M. Yamakawa, "Morphology, function and pathology of follicular dendritic cells", Pathol. Int., 46: 807-833 (1996).
Witkop, Jr., C.J. et al., "Hereditary Mucoepithelial Dysplasia: A Disease Apparently of Desmosome and Gap Junction Formation", Am. J. Hum. Genet., 31: 414-427 (1979).
Suster, S. and C.A. Moran, "Chordomas of the Mediastinum: Clinicopathologic, Immunohistochemical, and Utrastructual Study of Six Cases Presenting as Posterior Mediastinal Masses", Hum. Pathol., 26: 1354-1362 (1995).
Mrak, R.E. and G.F. Baker, "Granular cell basal cell carcinoma", J. Cutan. Pathol., 14: 37-42 (1987).
Sugrue, S.P. and P. Ouyang, (Direct Submission), GenBank Sequence Database (Acession U77717), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1684842; GI 1684843).
Franke, W.W. et al., "Isolation and symmetrical splitting of desmosomal structuresin 9 M urea", Eur. J. cell Biol, 32: 117-130 (1983).
Stillwell, W. and K. Doram, "Measurement of Transmembrane Proton Diffusion Using Two Liposome-Sequestered pH Indicator Dyes", Biochem. Biophys. Res. Comm., 93: 326-332 (1980).

Affiliated with

Also associated with

Rating

Human pinin splice variant does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Human pinin splice variant, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Human pinin splice variant will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-270015