RNA detection assays

Details RNA detection assays RNA detection assays

2011-05-03

2011-05-03

Chunduru, Suryaprabha (Department: 1637)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S006120, C530S350000

Reexamination Certificate

active

07935800

ABSTRACT:
The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. In some embodiments, the 5′ nuclease activity of a variety of enzymes is used to cleave a target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

REFERENCES:
patent: 5244797 (1993-09-01), Kotewicz et al.
patent: 5268289 (1993-12-01), Dahl et al.
patent: 5459055 (1995-10-01), Jendrisak et al.
patent: 5466591 (1995-11-01), Abramson et al.
patent: 5500370 (1996-03-01), Jendrisak et al.
patent: 5541311 (1996-07-01), Dahlberg et al.
patent: 5614402 (1997-03-01), Dahlberg et al.
patent: 5795762 (1998-08-01), Abramson et al.
patent: 5795763 (1998-08-01), Dahlberg et al.
patent: 5837458 (1998-11-01), Minshull et al.
patent: 5843669 (1998-12-01), Kaiser et al.
patent: 5846717 (1998-12-01), Prudent et al.
patent: 5874283 (1999-02-01), Harrington et al.
patent: 5985557 (1999-11-01), Prudent et al.
patent: 5994069 (1999-11-01), Hall et al.
patent: 6001567 (1999-12-01), Brow et al.
patent: 6090606 (2000-07-01), Kaiser et al.
patent: WO 97/27214 (1997-07-01), None
patent: WO 98/27230 (1998-06-01), None
patent: WO 98/31837 (1998-07-01), None
patent: WO 98/42873 (1998-10-01), None
patent: WO 99/65927 (2000-01-01), None
patent: WO 00/18906 (2000-04-01), None
patent: WO 01/90337 (2001-11-01), None
Kaiser et al., J. Biol. Chem., 274:21387 [1999].
Lyamichev et al., Nat. Biotechnol., 17:292 [1999].
Lyamichev et al., Science 260:778 [1993].
Kwiatkowski et al., Molec. Diagn., 4:353 [1999].
Xu et al., J. Biol. Chem., published online as 10.1074/jbc.M909135199 at www.jbc.org/pips/pips.2.shtml, May 9, 2000.
Doherty et al., Nucl. Acid. Res., 24:2488 [1996].
Marmur and Lane, Proc. Natl. Acad. Sci. USA 46:453 [1960].
Doty et al., Proc. Natl. Acad. Sci. USA 46:461 [1960].
Nielsen et al., Anticancer Drug Des. 8:53 [1993].
Mullis and Faloona, Methods in Enzymology, 155:335 [1987].
Saiki et al., Science 230:1350 [1985].
Eom et al., Nature 382:278 [1996].
Minnick et al., J. Biol. Chem., 271:24954 [1996].
Polesky et al., J. Biol. Chem., 267:8417 [1992].
Kiefer et al., Nature 391:304 [1998].
Ollis et al., Nature 313:762 [1985].
Kim et al., Nature 376:612 [1995].
Korolev et al., Proc. Natl. Acad. Sci., 92:9264 [1995].
Doublie et al., Nature 391:251 [1998].
Pelletier et al., Science 264:1891 [1994].
Ceska et al., Nature 382:90 [1996].
Hwang et al., Nat. Struct. Biol., 5:707 [1998].
Del Rio et al., Biotechniques 17:1132 [1994].
M.J.R. Stark, Gene 5:255 [1987].
Studier and Moffatt, J. Mol. Biol., 189:113 [1986].
Sambrook et al. Molecular Cloning, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, pp. 1.63 1.69 [1989].
Engelke et al., Anal. Biochem., 191:396 [1990].
Myers and Gelfand, Biochemistry 30:7661 [1991].
Johnson et al., Science 269:238 [1995].
Higuchi, in PCR Technology, H. A. Erlich, ed., Stockton Press, New York. pp. 61 70 [1989].
Brautigam et al., Curr. Opin Struc Biol. 8(2):54-63 (1998).
Urs et al., Ada Crystallogr D. Biol. Crystallogr 55(Pt 12):1971-7 (1999).
Hall et al., PNAS 97:8272-8277 (2000).
Xu et al., J Biol. Chem. 275:20949-20955 (2000).
Van Deuren et al., J. Int. Fed. Clin. Chem., 5:216 [1993].
Van Deuren et al., J. Inf. Dis., 169:157 [1994].
Perenboom et al., Eur. J. Clin. Invest., 26:159 [1996].
Guidotti et al., Immunity 4:25 [1996].
Grant et al., Transplantation 62:910 [1996].
Mellors et al., Science 272:1167 [1996].
Saag et al., Nature Medicine 2:625 [1996].
Lyamichev et al., Prot. Natl. Acad. Sci., 96:6143 [1999].
Li et al., Protein Sci., 7:1116 [1998].
Saiki et al., Science 230:1350 [1985].
Joyce and Steitz, Trends in Biochemical Science 12:288 [1987].
Breese et al., Science 260:352 [1993].
Polesky et al., J. Biol. Chem., 265:14579 [1990].
Pandey et al., Eur. J. Biochem., 214:59 [1993].
Holm and Sander, J. Mol. Biol., 233:123 [1993].
Holm and Sander, Science 273:595 [1996].
Li et al., EMBO J., 17:7514 [1998].
May et al., Proc. Natl. Acad. Sci., 83:8957 [1986].

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