Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2011-01-11
2011-01-11
Powers, Fiona T (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
07868182
ABSTRACT:
A novel solventless process is described for the preparation of imidazole-2-thiones. The new solventless process tolerates a variety of bases as co-reactants which introduces feedstock flexibility into the process while the solventless feature renders the process more environmentally friendly by eliminating volatile organic solvents from the process, reducing energy consumption (associated with solvent recovery and/or recycling), and allows shorter reaction time and workup. Furthermore, the elimination of solvents enhances workplace safety by obviating the need for flammable and/or toxic solvents.
REFERENCES:
patent: 5030644 (1991-07-01), Baldwin et al.
patent: 5077414 (1991-12-01), Arduengo, III
patent: 5104993 (1992-04-01), Arduengo, III
patent: 5162482 (1992-11-01), Arduengo, III
patent: 5198457 (1993-03-01), Yarrington
patent: 5554211 (1996-09-01), Bokisa
patent: 5962586 (1999-10-01), Harper
patent: 6395948 (2002-05-01), Hope et al.
patent: 7115748 (2006-10-01), Grast
patent: 2003/0094380 (2003-05-01), Moulton
Nguyen et al.,“Ionic Liquids as Catalytic “Green” Reactants and Solvents for Nucleophilic Conversion of Fatty Alcohols to Alkyl Halides”, Green Chemistry, 5, 303-305, 2003.
Freemantle, “Designer Solvents: Ionic Liquids May Boost Clean Technology Development”, Chemical and Engineering News, 32-37, Mar. 30, 1998.
Holbrey, “Industrial Applications of Ionic Liquids”, Chemistry Today, 35-37, Jun. 2004.
Tao et al., “Unexpected Microwave Reaction of 1,3-Disubstituted Imidazolium Salts: A Novel Synthesis of 1,3-disubstituted Imidazole-2-thiones”, Synthetic Communications, 37(3),399-408, 2007.
Karkhanis et al., STN, file CASREACT, Abstract No. 103:53997, 1985, “Thiono Compounds. 5. Preparation and Oxidation of Some Thiono Derivatives of Imidazoles”.
Lei et al., STN, file CASREACT, Abstract No. 145;83328, 2005, CN 1680337, “Microwave Irradation Solvent-Free Method for Synthesis of 1,3-Disubstituted 4-Imidazoline-2-thiones”.
Parnham et al., “1-Alkyl-3-Methyl Imidazolium Bromide Ionic Liquids in the Ionothermal Synthesis of Aluminum Phosphate Molecular Sieves”, Chem. Mater., 18(20), 4882-4887, 2006.
Nelson, “Are Ionic Liquids Green Solvents?”, 818 ACS Symposium Series, 30-41, (American Chemical Society 2002).
Freemantle, “Eyes On Ionic Liquids”, Chemical and Engineering News, 78(20), 37-50, May 15, 2000.
Ren et al., Chemical Abstracts, Abstract No. 2002:617123, 2002.
Chowdhury et al., “Reactivity of Ionic Liquids”, Tetrahedron , 63, 2263-2389, available online Dec. 8, 2006.
Trzhtsinskaya, Bella V. et al., “Imidazole-2-Thiones: Synthesis, Structure, Properties”, Journal of Sulfur Chemistry, 10(4), 389-421, Jun. 1991.
Benac, B.; Burgess, E. M.; Arduengo, III, A. J. “The Synthesis of 1,3-Dimethylimidazole-2-thione”, Organic Syntheses, vol. 64, pp. 92-95, 1986.
Biegel, L. B. et al.. “Subchronic Toxicity Study in Rats with 1-Methy1-3-propylimidazole-2-thione (PTI): Effects on the Thyroi” Fundamental and Applied Tox., 27, 185-94, 1995.
Arduengo, III, A. J. et al. “Electron Distribution in a Stable Carbene” J. Am. Chem. Soc. 116, 6812-22, 1994.
LandOfFree
Solventless one-step process for the production of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Solventless one-step process for the production of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Solventless one-step process for the production of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2693856