Oxygen-assisted fermentation process

Details Oxygen-assisted fermentation process Oxygen-assisted fermentation process

2011-07-26

2011-07-26

Ware, Deborah K. (Department: 1651)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

C435S252100, C435S283100, C435S287100, C435S287500, C435S813000, C435S818000

Reexamination Certificate

active

07985574

ABSTRACT:
A fermentation process uses substantially pure oxygen. The oxygen is the only reactive gas which is injected into a fermentation vessel. The oxygen is moved through the vessel solely by its own pressure. The process can be used with both mechanically-agitated and air-lifted fermenters. The mechanically-agitated fermenter includes an analyzer for measuring oxygen concentration in the exhaust line, and adjusting the flow of fresh oxygen into the vessel accordingly. In the air-lifted fermenter, an analyzer measures the oxygen concentration in the head space of the vessel, and operates valves which either recycle the gas from the head space, or vent that gas to the outside, according to the measured concentration. A stream of nitrogen is periodically injected into the vessel to drive out carbon dioxide and other gases, to control the pH of the fermentation medium. The present invention substantially improves the efficiency of a commercial fermentation process.

REFERENCES:
patent: 4169010 (1979-09-01), Marwil
patent: 4426450 (1984-01-01), Donofrio
patent: 4808534 (1989-02-01), Schick et al.
patent: 4992370 (1991-02-01), Kalina
patent: 5158890 (1992-10-01), Kalina
patent: 5198362 (1993-03-01), Forsyth et al.
patent: 5424196 (1995-06-01), Cambiaghi
patent: 5798254 (1998-08-01), Cheng
patent: 5972661 (1999-10-01), Kubera et al.
patent: 5985652 (1999-11-01), Cheng
patent: 6280996 (2001-08-01), Cheng
patent: 6482373 (2002-11-01), Hannaford et al.
patent: 6579085 (2003-06-01), Satchell et al.
patent: 6692661 (2004-02-01), Bedetti
patent: 7718405 (2010-05-01), Brahmbhatt
patent: 2002/0115132 (2002-08-01), Ho et al.
patent: 2003/0080446 (2003-05-01), Cheng
patent: 0341878 (1989-04-01), None
patent: 1038948 (2000-03-01), None
patent: 1457571 (1974-01-01), None
Chen, Yinliang et al, J. Chem. Tech. Biotechnol. 67, “Continuous Production of Thrombomodulin from aPichia pastorisFermentation”., pp. 143-148 (1996).
International Search Report, (2005).

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