Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2011-05-24
2011-05-24
Jarrell, Noble (Department: 1624)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
07947827
ABSTRACT:
Pharmaceutical formulation for the prophylaxis, pretreatment and treatment of a poisoning caused by exposure to (either singly or as a mixture of agents) organophosphorus cholinesterase inhibitors, vesicating agents, polycyclic aromatic hydrocarbons, and aflatoxin B1. This invention is characterized by active substance comprised of a metaloporphyrin molecule with an associated metal moiety (Cu, Mg) of suitable purity and chemical composition to provide a bioavailable oral dosage form to attain predictable concentrations in target tissues and bodily fluids (plasma, bronchial secretions, etc.) sufficient to counteract the effects of toxic substances through chemical complexation or catalysis of toxin degradation. Although these metaloporphyrins are semisynthetic products of chlorophyll, the preferred starting material is chlorophyll a (Chla) extracted and purified fromSpirulina pacificaor other sources. A specific method is invented to achieve a critical combination of purity and yield beyond those currently available.
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Bailey, Jr. George S.
Jubert Carole
Jarrell Noble
Klarquist & Sparkman, LLP
State of Oregon Acting By and Through The State Board of Higher
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