Folate mimetics and folate-receptor binding conjugates thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S248000, C514S251000, C514S262100, C514S264100, C544S183000, C544S236000, C544S256000, C544S257000, C544S280000

Reexamination Certificate

active

07875612

ABSTRACT:
A cell population expressing folate receptors is selectively targeted with a non-peptide folic acid analogue. The non-peptide folic acid analogue is conjugated to a diagnostic or therapeutic agent to enable selective delivery of the agent to the targeted cell population.

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