Imaging agents for functional imaging of lymphatic structures

Details Imaging agents for functional imaging of lymphatic structures Imaging agents for functional imaging of lymphatic structures

2011-01-25

2011-01-25

Jones, D L (Department: 1618)

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Diagnostic or test agent produces in vivo fluorescence

C424S009100

Reexamination Certificate

active

07875260

ABSTRACT:
Novel imaging agents targeted to a lymph vascular cell receptor and a hyaluranon cell receptor are disclosed. The disclosed imaging agents incorporate biological molecules such as hyaluronic acid which bind to the receptors. Lymph vascular cell receptor expression may be related to the beginnings of tumor formation. As such, embodiments of the imaging agents may be used to stain lymph structures for detailed imaging of lymph architecture as well as serving as potential markers for tumor angiogenesis, tumor metastases, etc.

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