Pyrazolo[3,4-d]pyrimidine compounds

Details Pyrazolo[3,4-d]pyrimidine compounds Pyrazolo[3,4-d]pyrimidine compounds

2011-06-21

2011-06-21

Moore, Susanna (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S262000

Reexamination Certificate

active

07964607

ABSTRACT:
The invention provides PDE9-inhibiting compounds of Formula (I),and pharmaceutically acceptable salts thereof, wherein R, R1, R2and R3are as defined herein. Pharmaceutical compositions containing the compounds of Formula I, and uses thereof in treating neurodegenerative and cognitive disorders, such as Alzheimer's disease and schizophrenia, are also provided.

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patent: 2004/0259870 (2004-12-01), Feng et al.
patent: 1460077 (2004-09-01), None
patent: 02085904 (2002-10-01), None
patent: 2004037176 (2004-05-01), None
Wunder et al., Mol. Pharmacol., vol. 28, No. 6, (2005), pp. 1776-1781.
van der Staay et al., Neuropharmacology, vol. 55 (2008), pp. 908-918.

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