Compounds and methods for leukotriene biosynthesis inhibition

Details Compounds and methods for leukotriene biosynthesis inhibition Compounds and methods for leukotriene biosynthesis inhibition

2011-03-29

2011-03-29

Chu, Yong (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S456000, C548S143000, C549S399000

Reexamination Certificate

active

07915298

ABSTRACT:
This invention provides novel salt and crystalline forms thereof of (−)4-(4-fluorophenyl)-7-[({5-[1-hydroxy-1-(trifluoromethyl)propyl]-1,3,4-oxadiazol-2-yl}amino)-methyl]-2H-chromen-2-one. The compounds are 5-LO inhibitors and are useful for treatment of conditions such as asthma, allergic rhinitis, COPD, and atherosclerosis.

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