Simultaneous quantification of nucleic acids in diseased cells

Details Simultaneous quantification of nucleic acids in diseased cells Simultaneous quantification of nucleic acids in diseased cells

2011-04-05

2011-04-05

Johannsen, Diana B (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091200, C435S091510, C536S024310, C536S024330, C536S025320

Reexamination Certificate

active

07919247

ABSTRACT:
A process for assessing mitochondrial toxicity of a compound that includes contacting nucleic acids from a host with an amplification reaction mixture that contains at least two primers that provide detectable signals, wherein:a first primer provides a first detectable signal upon amplification of a host mitochondrial nucleic acid;a second primer provides a second detectable signal upon amplification of a host nuclear nucleic acid; andcomparing the first and second detectable signals.

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