Arthroscopic irrigation solution and method for peripheral...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

07973068

ABSTRACT:
A method and solution for perioperatively inhibiting a variety of pain and inflammation processes during arthroscopic procedures. The solution preferably includes a vasoconstrictor that exhibits alpha-adrenergic activity and one or more additional pain and inflammation inhibitory agents at dilute concentration in a physiologic carrier, such as saline or lactated Ringer's solution. The solution is applied by continuous irrigation of a wound during a surgical procedure for peripheral vasoconstriction and inhibition of pain and/or inflammation while avoiding undesirable side effects associated with systemic application of larger doses of the agents.

REFERENCES:
patent: 4587257 (1986-05-01), DeSantis et al.
patent: 5124392 (1992-06-01), Robertson et al.
patent: 5212196 (1993-05-01), House et al.
patent: 5523316 (1996-06-01), Gan et al.
patent: 5582190 (1996-12-01), Slavin et al.
patent: 5624893 (1997-04-01), Yanni
patent: 5756503 (1998-05-01), Burke et al.
patent: 5767105 (1998-06-01), Peyman
patent: 5800385 (1998-09-01), Demopulos et al.
patent: 5811446 (1998-09-01), Thomas
patent: 5843016 (1998-12-01), Lugnani et al.
patent: 5858017 (1999-01-01), Demopulos et al.
patent: 5860950 (1999-01-01), Demopulos et al.
patent: 5942241 (1999-08-01), Chasin et al.
patent: 5972326 (1999-10-01), Galin et al.
patent: 6218428 (2001-04-01), Chynn
patent: 6248345 (2001-06-01), Goldenheim et al.
patent: 6261279 (2001-07-01), Demopulos et al.
patent: 7091181 (2006-08-01), Demopulos et al.
patent: 2040510 (1972-02-01), None
patent: 0 160 191 (1985-06-01), None
patent: 0 166 937 (1986-01-01), None
patent: 0 424 059 (1991-04-01), None
patent: 0 538 469 (1993-04-01), None
patent: WO 92/14453 (1992-09-01), None
patent: WO 92/17171 (1992-10-01), None
patent: WO 95/10280 (1995-04-01), None
patent: WO 95/16449 (1995-06-01), None
patent: WO 97/21445 (1997-06-01), None
patent: WO 98/38997 (1998-09-01), None
patent: WO 99/24023 (1999-05-01), None
patent: WO 00/38684 (2000-07-01), None
Eija et al. (Amitriptyline effectively relieves neuropathic pain following treatment of breast cancer, 1995, Pain, vol. 64, pp. 293-302.
Goodman and Gilman's The Pharmacological Basis of Therapeutics, 10th edition, pp. 9 and 710-712.
Phillips (Treatment of experimental poly-D-lysine arthritis in rabbits by non-steroidal anti-inflammatory compounds, Agents and Action, vol. 11, 3 (1981), pp. 260-264).
Kostamovaara (British Journal of Anaesthesia, Sep. 1998; 81; pp. 369-372).
Liou, Shiow-Wen, et al., “The Effect of Intracameral Adrenaline Infusion on Pupil Size, Pulse Rate, and Blood Pressure During Phacoemulsification,” (14)4:357-361 (1998).
Liou, Shiow-Wen, et al., “Maintenance of Mydriasis with One Bolus of Epinephrine Injection During Phacoemulsification,” 17(3):249-253 (2001).
Grond, S., et al., “Inhibition of Synovial Plasma Extravasation by Preemptive Administration of an Antiinflammatory Irrigation Solution in the Rat Knee,”Anesth Analg92:1301-6 (2001).
Frank, R.G., et al., “Antidepressent Analgesia in Rheumatoid Arthritis,”J Rheumatol15:1632-1638 (1988).
Henslee, T.M., et al., “Vasoconstrictive Agents Commonly Used in Combination with Local Anesthetics: A Literature Review,”The Journal of Foot Surgery26(6):504-510 (1987).
Gyrn et al.. “Intra-articular bupivacaine plus adrenaline for arthroscopic surgery of the knee,”Acta. Anaesthesiol. Scand.36:643-646 (1992).
Allen et al., “Postarthroscopy Analgesia With Intraarticular Bupivacaine/Morphine,”Anesthesiology79:475-480 (1993).
Massey et al.. “Serum Lidocaine Levels During Arthroscope Using Continuous Irrigation With Lidocaine,”Clin. Orthop.229:182-184 (1988).
Tsai et al., “Arthroscopic surgery of the knee in local anaesthesia,”Arch. Orthop. Trauma Surg.112:136-138 (1993).
Klein, “Tumescent Liposuction and Improved Postoperative Care Using Tumescent Liposuction Garments™,”Cosmetic Dermatology13:329-338 (1995).
Klein, “Tumescent Technique for Local Anesthesia Improves Safety in Large-Volume Liposuction,”Plast.Reconstr.Surg.92:1085-1098 (1993).
Klein et al.. “The Tumescent Technique: Anesthesia and Modified Liposuction Technique,”Dermatologic Clinics8:425-437 (1990).
Badner et al., “Addition of Morphine to Intra-Articular Bupivacaine Does Not Improve Analgesia Following Knee Joint Replacement,”Regional Anesthesia22:347-350 (1997).
Debruyne et al., “Prilocaine in arthroscopy: Clinical pharmacokinetics and rational use,”Clin. Pharmacol. Ther.38:549-553 (1985).
Saunders et al.. “Washout of local anesthetic during arthroscopy,”Arthroscopy4:90-92 (1998) (abstract only).
Wredmark et al., “Arthroscopy Under Local Anaesthesia Using Controlled Pressure-Irrigation with Prilocaine,”J.Bone Joint Surg. [Br.]64:583-585 (1982).
Pauwels et al., “Promotion of cell growth by stimulation of cloned human 5-HT1D receptor sites in transfected C6-glial cells is highly sensitive to intrinsie activity at 5-HT1D receptors,”Naunyn. Schmiedeberges. Arch. Pharmacol.354:136-144 (1996).
Noorily et al., “Intranasal anesthetic effects of lidocaine and tetracaine compared.”Otolaryngol. Head Neck Surg.113:370-374 (1995).
Noorily et al., “Cocaine, lidocaine, tetracaine: which is best for topical nasal anesthesia?”Anesth. Analg.81:724-727 (1995).
Tschernko et al., “Clonidine added to the anesthetic solution enhances analgesia and improves oxygenation after intercostal nerve block for thoracotomy,”Anesth. Analg.87:107-111 (1998).
Taittonen et al., “Effect of clonidine and dexmedetomidine premedication on perioperative oxygen consumption and haemodynamic state,”British Journal of Anaesthesia78:400-406 (1997).
Corbett et al., “Intraocular adrenaline maintains mydriasis during cataract surgery,”Br. J. Ophthalmol.78:95-98 (1994) (abstract only).
Gaumann et al., “Hyperpolarizing afterpotentials in C fibers and local anesthetic effects of clonidine and lidocaine,”Pharmacology48:21-29 (1994).
Gillart et al., “Effects of Local Clonidine for Prolongation of Akinesia After Peribular Block,”Anesthesiology31:A941-A942 (1994).
Reinhart et al., “Postoperative analgesia after peripheral nerve block for podiatric surgery: clinical efficacy and chemical stability of lidocaine alone versus lidocaine plus clonidine,”Anesth. Analg.83:760-765 (1996).
Talke et al., “Effects of perioperative dexmedetomidine infusion in patients undergoing vascular surgery,”Anesthesiology82:620-633 (1995).
Kanto, “The place of alpha-2-agonists in anaesthesioloay of today,”Acta. Anaesthesiol. Scand.41:4-5 (1997).
Pertovaara. “Antinociception induced by alpha-2-adrenoceptor agonists, with speical emphasis on medetomidine studies,”Prog. Neurobiol.40:691-709 (1993).
Smith et al.. “Monitored Anesthesia Care,”Int. Anesthesiol. Clin.32:99-112 (1994).
Ishiyama et al.. “Mechanisms of dexmedetomidine-induced cerebrovascular effects in canine in vivo experiments,”Anesth. Analg.81:1208-1215 (1995).
Grond et al.. “Inhibition of synovial plasma extravasation by preemptive administration of an antiinflammatory irrigation solution in the rat knee,”Anesth. Analg.92:1301-1306 (2001).
Ruffolo et al., “Receptor interactions of imidazolines. IX. Cirazoline is an alpha-1 adrenergic agonist and an alpha-2 adrenergic antagonist,”J. Pharmacol. Exp. Ther.222:29-36 (1982).
Willems et al., “Pharmacological evidence that alpha1-and alpha2-adrenoceptors mediate vasoconstriction of carotid arteriovenous anastomoses in anaesthetized pigs,”Br. J. Pharmacol.127: 1263-1271 (1999) (abstract only).
McCarthy et al., “Comparative neuropharmacology of dihydroergotamine and sumatriptan (GR 43175),”Headache29:420-422 (1989) (abstract only).
Van den Berg et al., “Ergotism leading to threatened limb amputation or to d

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Arthroscopic irrigation solution and method for peripheral... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Arthroscopic irrigation solution and method for peripheral..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Arthroscopic irrigation solution and method for peripheral... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2661589

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.