Pyrrolotriazine kinase inhibitors

Details Pyrrolotriazine kinase inhibitors Pyrrolotriazine kinase inhibitors

2011-07-19

2011-07-19

Balasubramanian, Venkataraman (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C514S243000

Reexamination Certificate

active

07982033

ABSTRACT:
The invention provides compounds of formula Iand pharmaceutically acceptable salts thereof.The formula I compounds inhibit tyrosine kinase activity of Trk receptors such as TrkA, TrkB, TrkC or Flt-3 thereby making them useful as anticancer agents.

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