Inhibitors of plasma kallikrein

Details Inhibitors of plasma kallikrein Inhibitors of plasma kallikrein

2011-07-12

2011-07-12

Nolan, Jason M (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S443000, C514S419000, C514S471000, C514S448000, C514S423000, C514S406000, C514S365000, C514S343000, C514S336000

Reexamination Certificate

active

07977380

ABSTRACT:
The present invention provides compounds that inhibit the activity of plasma kallikrein (PK) and methods of preventing and treating the formation of thrombin during or after a PK dependent disease or condition, for example, after fibrinolysis treatment.

REFERENCES:
patent: 5998424 (1999-12-01), Galemmo, Jr. et al.
patent: 6337344 (2002-01-01), Defossa et al.
patent: 7625944 (2009-12-01), Sinha et al.
patent: WO 2008/016883 (2008-02-01), None
International Search Report mailed on Feb. 6, 2008, for PCT Application No. PCT/US07/74761 filed on Jul. 30, 2007, 3 pages.

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