Modified live Aeromonas hydrophila vaccine for aquatic...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

Reexamination Certificate

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C424S234100, C424S235100, C424S093200, C424S009200

Reexamination Certificate

active

07988977

ABSTRACT:
Safe and effective live vaccines againstAeromonas hydrophilaof fish were created through the induction of rifampicin resistance in nativeAeromonas hydrophilaisolates; these including rifampicin-resistant mutants NRRL-B-50040 and NRRL-B-50041. Single immersion exposure of fish stimulated acquired immunity against virulentAeromonas hydrophilainfection.

REFERENCES:
patent: 6248329 (2001-06-01), Chandrashekar et al.
Ellis (Chapter 29 of Vaccines, Plotkin, et al. (eds) WB Saunders, Philadelphia, 1998, especially p. 571, paragraph 2).

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