6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S253040, C514S303000, C544S127000, C544S333000, C544S362000, C546S020000, C546S118000

Reexamination Certificate

active

07932251

ABSTRACT:
The present invention relates to 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives having the general Formula Ito pharmaceutical compositions comprising the same as well as to the use of these derivatives for the preparation of a medicament for the treatment of cathepsin S related diseases such as atherosclerosis, obesity, inflammation and immune disorders, such as rheumatoid arthritis, psoriasis, cancer, and chronic pain, such as neuropathic pain.

REFERENCES:
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patent: 1724264 (2006-11-01), None
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patent: WO 2004/000819 (2004-12-01), None
patent: WO 2004/000843 (2004-12-01), None
patent: WO 2005/085210 (2005-09-01), None
patent: WO 2007/080191 (2007-07-01), None
patent: WO 2009/010491 (2009-01-01), None
Yasuda et al. Advanced Drug Delivery Reviews vol. 57, p. 973-993 (2005).
International Search Report (PCT/US 2007/050356) for mail date Mar. 16, 2007, 2 pages.
Written Opinion of the International Searching Authority for PCT/US2007/050356, 5 pages.
International Search Report (PCT/EP2010/050418) for mail date Mar. 1, 2010, 2 pages.
International Search Report (PCT/EP2008.059172) for mail date Oct. 17, 2008, 3 pages.
Written Opinion of the International Searching Authority for PCT/EP2008.059172), 5 pages.

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