Stable salt of 3′-phosphoadenosine...

Details Stable salt of 3′-phosphoadenosine... Stable salt of 3′-phosphoadenosine...

2011-01-04

2011-01-04

Lewis, Patrick T (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S025300, C536S027100, C536S027110

Reexamination Certificate

active

07863438

ABSTRACT:
The present invention provides a stable salt of 3′-phosphoadenosine 5′-phosphosulfate (PAPS) and a production method therefor.The present invention is directed to a stable salt of PAPS (amine salt), which is formed between PAPS and an amine compound, and to a method for producing a stable salt of PAPS, which includes adding an amine compound to an aqueous PAPS solution in an amount by mole equal to or greater than that of PAPS, and lyophilizing the resultant solution.The present invention has first realized production of a solid-form PAPS salt having considerably improved stability through a very simple technique. Since the thus-produced amine salt of PAPS is very stable, the salt can be stored or employed without taking much care about decomposition thereof at ambient temperature.

REFERENCES:
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patent: 2002 249497 (2002-09-01), None
patent: 2003 55395 (2003-02-01), None

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