Certain 7(o-amino-methyl- or methylaminomethylphenyl- or cyclohe

Details Certain 7(o-amino-methyl- or methylaminomethylphenyl- or cyclohe Certain 7(o-amino-methyl- or methylaminomethylphenyl- or cyclohe

1976-06-11

1978-07-11

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544 26, 424246, C07D50136, A61K 31545

Patent

active

041003462

ABSTRACT:
Certain 7-acylamido-3-[1-carboxymethyl-(or ethyl- or propyl-)-tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids and their salts and easily hydrolyzed esters of the 4-carboxyl group were synthesized and found to be potent antibacterial agents which exhibited good aqueous solubility. A preferred embodiment was 7-(2-aminomethylphenylacetamido)-3-(1-carboxymethyltetrazol-5-ylthiomethyl )-3-cephem-4-carboxylic acid.

REFERENCES:
patent: 3819623 (1974-06-01), Takano et al.

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