Compounds and methods of use thereof for assaying...

Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus containing

Reexamination Certificate

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C435S018000, C435S019000, C568S016000, C554S078000

Reexamination Certificate

active

07989663

ABSTRACT:
Fluorogenic lysophosphatidic acid derivatives which can be used as substrates in a continuous, fluorogenic assay that can be performed in microtiter plates. The assays permit measuring LysoPLD activity levels in normal events such as pregnancy or disease states such as cancer. In addition, the present invention can be adopted to high throughout screening (HTS) for identification of potential inhibitors of lysoPLD activity.

REFERENCES:
patent: 6399392 (2002-06-01), Haugland
patent: 2004/0053893 (2004-03-01), Kishimoto
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