Use of anti-tissue factor antibodies for treating thromboses

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

Reexamination Certificate

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C424S133100, C424S141100, C424S143100, C514S013700, C514S014300

Reexamination Certificate

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07968094

ABSTRACT:
Disclosed is a method for preventing or treating thrombosis in a mammal such as a primate and particularly a human patient. A preferred method includes administering to the mammal a therapeutically effective amount of at least one humanized antibody, chimeric antibody, or fragment thereof that binds specifically to human tissue factor (TF). Additional methods and kits are provided.

REFERENCES:
patent: 4644055 (1987-02-01), Kettner et al.
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 5122458 (1992-06-01), Post et al.
patent: 5168062 (1992-12-01), Stinski
patent: 5171662 (1992-12-01), Sharma
patent: 5216132 (1993-06-01), Basi
patent: 5223427 (1993-06-01), Edgington et al.
patent: 5225539 (1993-07-01), Winter
patent: 5385839 (1995-01-01), Stinski
patent: 5437864 (1995-08-01), Edgington et al.
patent: 5530101 (1996-06-01), Queen et al.
patent: 5534254 (1996-07-01), Huston et al.
patent: 5552300 (1996-09-01), Makrides et al.
patent: 5589173 (1996-12-01), O'Brien et al.
patent: 5639641 (1997-06-01), Pedersen et al.
patent: 5693762 (1997-12-01), Queen et al.
patent: 5766886 (1998-06-01), Studnicka et al.
patent: 5861267 (1999-01-01), Su
patent: 5869046 (1999-02-01), Presta et al.
patent: 5879677 (1999-03-01), del Zoppo
patent: 5889157 (1999-03-01), Pastan et al.
patent: 5958713 (1999-09-01), Thastrup et al.
patent: 5985279 (1999-11-01), Waldmann et al.
patent: 5986065 (1999-11-01), Wong et al.
patent: 5997867 (1999-12-01), Waldmann et al.
patent: 6001978 (1999-12-01), Edgington et al.
patent: 6054297 (2000-04-01), Carter et al.
patent: 6117639 (2000-09-01), Germann et al.
patent: 6245884 (2001-06-01), Hook
patent: 6274142 (2001-08-01), O'Brien et al.
patent: 6287366 (2001-09-01), Derive et al.
patent: 6309636 (2001-10-01), do Couto et al.
patent: 6331415 (2001-12-01), Cabilly et al.
patent: 6333167 (2001-12-01), Quinet et al.
patent: 6555319 (2003-04-01), Wong et al.
patent: 6593291 (2003-07-01), Green et al.
patent: 6610293 (2003-08-01), Fischer et al.
patent: 6677436 (2004-01-01), Sato et al.
patent: 6703494 (2004-03-01), Kirchhofer et al.
patent: 6986894 (2006-01-01), O'Brien et al.
patent: 7749498 (2010-07-01), Jiao et al.
patent: 7824677 (2010-11-01), Wong et al.
patent: 2002/0025508 (2002-02-01), Fechteler et al.
patent: 2002/0065327 (2002-05-01), Jiao et al.
patent: 2003/0082636 (2003-05-01), Wong et al.
patent: 2003/0087372 (2003-05-01), DelaCruz et al.
patent: 2003/0109680 (2003-06-01), Wong et al.
patent: 2003/0119075 (2003-06-01), Kirchhofer et al.
patent: 2003/0124117 (2003-07-01), Refino et al.
patent: 2003/0176664 (2003-09-01), Jiao et al.
patent: 2004/0033200 (2004-02-01), Ezban et al.
patent: 2004/0126816 (2004-07-01), Kirchhofer et al.
patent: 2004/0229282 (2004-11-01), Wong et al.
patent: 2005/0089929 (2005-04-01), Jiao et al.
patent: 2005/0271664 (2005-12-01), Wong et al.
patent: 2006/0039901 (2006-02-01), Jiao et al.
patent: 2006/0159675 (2006-07-01), Jiao et al.
patent: 2006/0235209 (2006-10-01), Jiao et al.
patent: 2009/0041766 (2009-02-01), Jiao et al.
patent: 2009/0092602 (2009-04-01), Jiao et al.
patent: 2009/0136501 (2009-05-01), Jiao et al.
patent: 2009/0252726 (2009-10-01), Jiao et al.
patent: 0 239 400 (1987-09-01), None
patent: 0 239 400 (1987-09-01), None
patent: 0 239 400 (1987-09-01), None
patent: 0 420 937 (1991-04-01), None
patent: 1 069 185 (2001-01-01), None
patent: 4-502408 (1992-05-01), None
patent: 1-503438 (1998-11-01), None
patent: 2001-516214 (2001-09-01), None
patent: WO-89/12463 (1989-12-01), None
patent: WO-90/07861 (1990-07-01), None
patent: WO-91/18019 (1991-11-01), None
patent: WO-94/05328 (1994-03-01), None
patent: WO-96/13593 (1996-05-01), None
patent: WO-96/13593 (1996-05-01), None
patent: WO-96/18105 (1996-06-01), None
patent: WO-96/40921 (1996-12-01), None
patent: WO-98/40408 (1998-09-01), None
patent: WO-98/51321 (1998-11-01), None
patent: WO-99/43713 (1999-09-01), None
patent: WO-00/18398 (2000-04-01), None
patent: WO-01/27079 (2001-04-01), None
patent: WO-01/30333 (2001-05-01), None
patent: WO-01/70984 (2001-09-01), None
patent: WO-01/70984 (2001-09-01), None
patent: WO-03/029295 (2003-04-01), None
patent: WO-03/037911 (2003-05-01), None
patent: WO-03/037911 (2003-05-01), None
patent: WO-2005/004793 (2005-01-01), None
patent: WO-2005/004793 (2005-01-01), None
patent: WO-2005/004793 (2005-01-01), None
patent: WO-2005/072126 (2005-08-01), None
patent: WO-2005/072126 (2005-08-01), None
Alberts et al. (2002).The Cell, Garland Science 4thedition, pp. 161, Fig. 3-42.
Albrecht et al. (1992). “An ELISA for Tissue Factor Using Monoclonal Antibodies,”Blood Coagulation and Fibrinolysis3:263-270.
Almus et al. (1990). “Properties of Factor VIIa/Tissue Factor Complexes in an Umbilical Vein Model,”Blood76(2):354-360.
Amirkhosravi et al. (2001).Suppl. To J. of Thrombosis and HaemostasisAbstract: OC1021.
Ardaillou et al. (1992). “Glomerular Tissue Factor Stimulates Thromboxane Synthesis in Human Platelets via Thrombin Generation,”Kidney International41:361-368.
Asadullah, K. et al. (Dec. 1999). “The Pathophysiological Role of Cytokines in Psoriasis,”Drugs of Today35(12):913-924.
Barstad et al. (1995). “Procoagulant Human Monocytes Mediate Tissue Factor/Factor VIIa-Dependent Platelet-Thrombus Formation when Exposed to Flowing Nonanticoagulated Human Blood,”Arteriosclerosis, Thrombosis, and Vascular Biology15(1):11-16 (1995).
Beers et al. (1999).The Merck Manual of Diagnosis and Therapy, 17thedition, Merck Research Laboratories, pp. 1654-1681.
Benedict et al. (Feb. 1995). “Monoclonal Antibody to Tissue Factor Inhibits Intravascular Thrombosis without Impairing Extravascular Hemostasis,”JACCAbstract 1012-1104, p. 366A.
Benhar et al. (1994). “Rapid Humanization of the Fv of Monoclonal Antibody B3 by Using Framework Exchange of the Recombinant Immunotoxin B3(Fv)-PE38,”Proc. Natl. Acad. Sci. USA91:12051-12055.
Bernhard, G.R. et al. (2001). “Efficacy and Safety of Recombinant Human Activated Protein C for Severe Sepsis,”The New England Journal of Medicine344:699-709.
Berzofsky, J.A. et al. (1993). “Immunogenicity and Antigen Structure,” Chapter 8 inFundamental Immunology, Paul, W.E. ed., Raven Press: New York, NY, p. 242.
Bird, R.E. et al. (Oct. 21, 1988). “Single-Chain Antigen-Binding Proteins,”Science242(4877):423-426.
Bjoern et al. (1991). “Human Plasma and Recombinant Factor VII,”The Journal of Biological Chemistry266(17):11051-10057.
Bokarewa et al. (Sep. 2002). “Intra-Articular Tissue Factor/Factor VII Complex Induces Chronic Arthritis,”Inflamm. Res.51(9):471-477.
Booy et al. (2006). “Monoclonal and Bispecific Antibodies as Novel Therapeutics,”Arch. Immunol. Ther. Exp.54:85-101.
Boulianne et al. (1984). “Production of Functional Chimeric Mouse/Human Antibody,”Nature312:643-646.
Broze, G.J., Jr. (1982). “Binding of Human Factor VII and VIIa to Monoytes,”J. Clin. Invest.The American Society for Clinical Investigation, Inc. 70:526-535.
Bruggemann et al. (1989). “The Immunogenicity of Chimeric Antibodies,”J. Exp. Med.170:2153-2157.
Busso, N. et al. (Mar. 2003). “Role of the Tissue Factor Pathway in Synovial Inflammation,”Arthritis Rheum.48(3):651-659.
Cacia et al. (1996). “Isomerization of an Aspartic Acid Residue in the Complementarity-Determining Regions of a Recombinant Antibody to Human IgE: Identification and Effect on Binding Affinity,”Biochemistry35:1897-1903.
Camerer et al. (2000). “Tissue Factor—And Factor X-Dependent Activation of Protease-Activated Receptor 2 by Factor VIIa,”Proc. Natl. Acad. Sci. USA97(10):5255-5260.
Carraway, M.S. et al. (May 1, 2003). “Blockade of Tissue Factor,”American Journal of Respiratory and Critical Care Medicine167(9):1200-1209.
Carson et al. (1985). “Monoclonal Antibodies against Bovine Tissue Factor, which Block Interaction with Factor VII,”Blood66(1):152-156.
Carson et al. (1987). “An Inhibitory Mo

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