Block alignment for microtomes

Details Block alignment for microtomes Block alignment for microtomes

2011-08-23

2011-08-23

Nguyen, Phong H (Department: 3724)

Cutting

With signal, scale, or indicator

Indicates tool position

C083S468000, C083S915500, C033S514200, C033S561100, C033S645000

Reexamination Certificate

active

08001876

ABSTRACT:
Systems and methods described herein for aligning a block in a microtome attempt to save time, money, and the sample by aligning a block in any rotary or cryostat microtome. One such device for aligning a block in a microtome has a knife holder component removably attached to a knife holder of the microtome and a pin alignment component extending vertically from the knife holder component in a direction substantially parallel to the block. The pin alignment component has a plurality of front pins extending from a front surface of the pin alignment component configured to slide in response to an angle of the block and a plurality of rear pins extending from a rear surface of the pin alignment component and coupled to the front pins. The rear pins are configured to indicate the extension of the front pins from the pin alignment component.

REFERENCES:
patent: 664118 (1900-12-01), Becker
patent: 2523647 (1950-09-01), Burk
patent: 4700600 (1987-10-01), Pickett
patent: 4878486 (1989-11-01), Slater
patent: 5082254 (1992-01-01), Hunnell et al.
patent: 5148729 (1992-09-01), Krumdieck
patent: 5161446 (1992-11-01), Holbl et al.
patent: 5282404 (1994-02-01), Leighton et al.
patent: 5711200 (1998-01-01), Thiem
patent: 6058824 (2000-05-01), Neymeyr
patent: 6160264 (2000-12-01), Rebiere
patent: 7066067 (2006-06-01), Hess
patent: 7146894 (2006-12-01), Hendrick et al.
patent: 2004/0020087 (2004-02-01), Fleming
patent: 2004/0244548 (2004-12-01), Zimmermann et al.
patent: 2005/0147538 (2005-07-01), Williamson, IV et al.
patent: 2005/0223862 (2005-10-01), Oberheim
patent: 2005/0279200 (2005-12-01), Duginske
patent: 2006/0219080 (2006-10-01), Heid
“Clinical Laboratory Technologists and Technicians,” Bureau of Labor Statistics, U.S. Department of Labor,Occupational Outlook Handbook, 2006-2007 Edition (accessed Dec. 15, 2006), http://www.bls.gov/oco/ocos096.htm.
Ellis, Roy, “Problems and ‘Did You Know's’ in Histophathological Technique,” IHC World, originally accessed on Dec. 31, 2006 [retrieved on May 11, 2011], 4 pp., Retrieved From the Internet: http://www. ihcworld.com/royellis/Problems/index.html.
“Certification,” American Society for Clinical Pathology, originally accessed on Dec. 14, 2006 [retrieved on May 11, 2011], 1 p., Retrieved From the Internet: http://www.ascp.org/certification/default.aspx.
“HM 340E,” Microm International, [retrieved on May 11, 2011], 1 p., Retrieved From the Internet: http://www.microm.de/microm%20homepage.html/home—e.hmtl.
“LMT F14—A Laser Microtome For Precise, Non-Contact Sectioning,” Rowiak-Products, Products, originally accessed on Dec. 12, 2006 [retrieved on May 11, 2011], 1 p., Retrieved From the Internet: http://.rowiak.com/products.htm.
“Histo Collimator,” Microm International, originally accessed on Dec. 13, 2006 [retrieved on May 11, 2011], 1 p., Retrieved From the Internet: http://www.microm.de/Microm%20Homepage/html/histo—collimator—e.html.
Urban, Glen L. and von Hippel, Eric, “Lead User Analyses For the Development of New Industrial Products,” Jun., 1986, 24 pp.
“Prostate Cancer Tests Might Miss One in Seven Cases,” UniSci, originally accessed on Dec. 15, 1006 [retrieved on May 11, 2011], 2 pp., http://www.unisci.com/stories/20013/0709012.htm.
“Laboratory Ergonomics: Microtomy,” Ergonomic Resources, originally accessed on Dec. 15, 2006 [retrieved on May 11, 2011], 6 pp., Retrieved From the Internet: http://www.dehs.umn.edu/ergo/lab/#microtomy.
American Society For Clinical Pathology, “About Us,” originally accessed on Dec. 12, 2006 [retrieved on May 11, 2011], 1 p., Retrieved From the Internet: http://www.ascp.org/aboutus/default.aspx.
Gschwendtner, A. and Mairinger, T., “How Thick is Your Section? The Influence of Section Thickness on DNA-Cytometry on Histological Sections,”Analytical Cellular Pathology, vol. 9, No. 1, Jul., 1995, 10 pp.
Gibbs, Hope J., “The Hidden Profession of Histotechnology,”Techniques, Oct. 2004 [retrieved on May 18, 2011], 27 pp., Retrieved From the Internet: http://www.acteonline.org/content.aspx?id=5746.
“Cell/Tissue Culture Supplies,” Global Industry Analysts, Oct. 1, 2010 [retrieved on May 12, 2011], 2 pp., Retrieved From the Internet: http://www.marketresearch. com/product/display. asp?productid=2876767&SID=77738459.
“Re: [Histonet] Block Alignment,” originally accessed on Dec. 13, 2006 [retrieved on May 12, 2011], 3 pp., Retrieved From the Internet: http;//www.histosearch.com/histonet/Mar05/RE.Histonetblockalignment.html.
Modern Pathology, “About the Journal,” originally accessed on Dec. 12, 2006 [retrieved on May 12, 2011], 5 pp., Retrieved From the Internet: http://www.nature.com/modpathol/about.html.
Thermo Scientific, “About Us,” originally accessed on Dec. 15, 2006 [retrieved on May 24, 2011], 1 p., Retrieved From the Internet: http;//www.thermo. com/com/cda/aboutus/home/0.1025—00.html.
“The Market For Tissue Microarrays,”Bioinformatics, Jul. 2003 [retrieved on May 12, 2011], 3 pp., Retrieved From the Internet: http;//www.the-infoshop.com/report/fb14859—tissue—microarrays.html.
“Trends and Emerging Technologies in Drug Discovery,” Dec. 29, 2005 [retrieved on May 12, 2011], 3 pp., Retrieved From the Internet: http://www.frost.com/prod/servlet/report-brochure.pag?id=F299-01-00-00-00.
“Repetitive Motion Disorders (RMD)—A Rapidly Increasing Problem For the Histoloty Laboratory of Tomorrow,” originally accessed Dec. 15, 2006 [retrieved on May 24, 2011], 3 pp., Retrieved From the Internet: http://www.hbu.de/rmd.htm.
“NCI-Frederick” [online], retrieved on Jun. 6, 2011, 2 pp., Retrieved From the Internet: http://www.ncifcrf.gove.

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