Chemistry: analytical and immunological testing – Clotting or clotting factor level tests
Reexamination Certificate
2011-07-12
2011-07-12
Alexander, Lyle A (Department: 1773)
Chemistry: analytical and immunological testing
Clotting or clotting factor level tests
C422S073000, C422S076000, C435S013000
Reexamination Certificate
active
07977106
ABSTRACT:
This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate the coagulation cascade. An artificial substrate for thrombin, the enzyme whose action results in clot formation is also provided. Clot formation is subsequently detected using a microfabricated sensor also housed within the cartridge which detects electrochemically the product of the thrombin reaction upon the synthetic substrate.
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Cheadle Rhonda J.
Lauks Imants R.
Maczuszenko Andrzej
Opalsky Cindra A. Widrig
Opalsky David
Abbott Point of Care Inc.
Alexander Lyle A
Katten Muchin & Rosenman LLP
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