Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1977-03-17
1978-07-11
Schwartz, Gerald A.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
C07C 4946, C07C 4980, C07C 4982
Patent
active
041001982
ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
REFERENCES:
derwent Farmdoc CPI No. 76109U-B (9-5-72).
Armitage Robert A.
Schwartz Gerald A.
The Upjohn Company
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