2,6-Methano-3-benzazocines

Details 2,6-Methano-3-benzazocines 2,6-Methano-3-benzazocines

1976-11-12

1978-07-11

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260283S, 260289C, 260288CF, 424258, C07D21504, C07D21508, C07D21536, C07D21548

Patent

active

041001648

ABSTRACT:
6(EQ)-R.sub.4 -1,2,3,4,5,6-Hexahydro-3-R.sub.1 -11(ax)-R.sub.3 -11(eq)-CH.sub.2 Z-2,6-methano-3-benzazocines, useful as analgesic agents and narcotic antagonists, and 1-R.sub.1 -2-Q-4a.alpha.-R.sub.3 -5.alpha.-R.sub.4 -1,2,3,4,4a,5,10,10a-octahydro-3,5-ethano- (and 3,5-ethano) benzo[g]quinolines, useful as analgesic agents, prepared by heating, with formic acid in an organic solvent or with certain ammonium formates in the absence of a solvent, certain 1,2,3,4,4a,5,10,10a-octahydro-2,5-methanobenzo[g]quinolines, the latter prepared by acid catalyzed cyclization of a 3-benzyl-2-azabicyclo[2.2.2]-oct-5-ene.

REFERENCES:
patent: 2524856 (1950-10-01), Schnider et al.
Toshitsugu et al., Chemical Abstracts, vol. 83: 206,127u, (1975).

Affiliated with

Also associated with

Rating

2,6-Methano-3-benzazocines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2,6-Methano-3-benzazocines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2,6-Methano-3-benzazocines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-261691