Medicinal and cosmetic compositions

Details Medicinal and cosmetic compositions Medicinal and cosmetic compositions

1989-07-12

1991-10-08

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 42, 5142328, 514255, 514320, 514422, 514468, A61K 3134

Patent

active

050554522

ABSTRACT:
A benzofuran derivative which is a compound of formula (I): ##STR1## wherein a to d each are 0 or 1, with a+b+c+d.gtoreq.2; R.sub.1 to R.sub.6 are each H or C.sub.1 -C.sub.6 alkyl; R.sub.7 is --CH.sub.2 OR.sub.8 (R.sub.8 =H, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 mono- or polyhydroxyalkyl), --COR.sub.9 (R.sub.9 =H, C.sub.1 -C.sub.6 alkyl, ##STR2## which is an amino acid or amino sugar residue or where R' and R" are H, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 mono- or polyhydroxyalkyl, C.sub.3 -C.sub.6 alkenyl or form a heterocycle) or OR.sub.10 (where R.sub.10 is H, C.sub.1 -C.sub.20 alkyl, C.sub.2 -C.sub.6 mono- or polyhydroxyalkyl or --OR.sub.10 is derived from a sugar) has retinoid type action and can be used in cosmetics (body and hair hygiene) and in medicine (treatment of dermatological conditions; atopy; degenerative diseases of connective tissue; or corneopathies).

REFERENCES:
patent: 4775663 (1988-10-01), Forestier et al.
Fry et al., J. Org. Chem., vol. 46, pp. 2177-2179 (1981).

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