Aqueous collagen composition

Details Aqueous collagen composition Aqueous collagen composition

1976-11-24

1979-02-20

Hayes, Lorenzo B.

Compositions: coating or plastic

Coating or plastic compositions

Proteinaceous material containing

106161, 2601237, C08L 8906

Patent

active

041405374

ABSTRACT:
The naturally occurring collagen is modified by removal of certain terminal peptide chains, which are described as telopeptides. The modified collagen, so derived, is described as atelopeptide collagen. Native collagen is immunogenic, while atelopeptide collagen is nonimmunogenic or possessed of a negligibly low level of immunogenicity.
The collagen in solution is then treated according to a specific regimen under conditions whereby the collagen slowly separates from solution while exposed to mild shear forces. This procedure results in the formation of a fibrous precipitate composed of regularly ordered fibers of collagen possessed of a ropelike structure. These resulting aggregates are referred to as native fibrous micropolymers (NFM). Once the regimen or procedure is completed, and the fiber mass has been formed, the fibrous micropolymers may be freed of salt, taken up in a different solution or modified. For example, cross-links may then be introduced to stabilize the fibers. The products find wide use as packing, membranes, fibers, bags, supports, integuments, and are especially suitable for biologic implantation or application.

REFERENCES:
patent: 3121049 (1964-02-01), Nishihara
patent: 3433864 (1969-03-01), Highberger et al.

Affiliated with

Also associated with

Rating

Aqueous collagen composition does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aqueous collagen composition, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aqueous collagen composition will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-256814