Nucleic acid probe and method for the rapid detection of typhoid

Details Nucleic acid probe and method for the rapid detection of typhoid Nucleic acid probe and method for the rapid detection of typhoid

1986-06-23

1991-10-08

Kepplinger, Esther L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 79, 435 34, 4353201, 435879, 536 27, 436501, C12Q 168, C12Q 104, C12N 1500

Patent

active

050553941

ABSTRACT:
This invention relates to a nucleic acid probe and method for the rapid detection of typhoid fever bacteria by use of a nucleic acid hybridization probe, equivalent to the DNA region encoding the Vi antigen of enteric bacteria such as Salmonella typhi, S. paratyphi C, or Citrobacter freundii, in a nucleic acid hybridization reaction with a clinical specimen containing typhoid fever bacteria.

REFERENCES:
Snellings et al., Journal of Bacteriology, vol. 145, No. 2, pp. 1010-1017, Feb. 1981).
Baron et al., in Genetic Engineering of Microorganisms for Chemicals (Ed. A. Hollander) Plenum Press N.Y. pp. 175-194 (1982).
Moseley et al., J. of Infect. Dis., vol. 142, No. 6, (Dec. 1980), pp. 892-898.

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