Electrolysis: processes – compositions used therein – and methods – Electrolytic analysis or testing – Involving enzyme or micro-organism
Patent
1997-06-11
2000-05-16
Tung, T.
Electrolysis: processes, compositions used therein, and methods
Electrolytic analysis or testing
Involving enzyme or micro-organism
204403, G01N 2726
Patent
active
060632593
ABSTRACT:
A thick-film sensing apparatus for nucleic acid determination and testing using potentiometric stripping analysis, including two methods for nucleic acid detection at the microfabricated strips, both methods being designed for use with the thick-film sensing apparatus. The present invention is applicable for broad use in nucleic acid analysis, particularly for measurement of nucleic acids (e.g., DNA and RNA), and their sequences and interactions, and for detection of DNA damage, at thick-film electrodes, based on stripping potentiometry.
REFERENCES:
patent: 4348477 (1982-09-01), Nakano et al.
patent: 4786373 (1988-11-01), Salobeimo et al.
patent: 5091299 (1992-02-01), Turner et al.
patent: 5096669 (1992-03-01), Lauks et al.
patent: 5120421 (1992-06-01), Glass et al.
patent: 5128015 (1992-07-01), Szuminsky
patent: 5269891 (1993-12-01), Colin
patent: 5292423 (1994-03-01), Wang
patent: 5296125 (1994-03-01), Glass et al.
patent: 5298129 (1994-03-01), Eliash
patent: 5312527 (1994-05-01), Mikkelsen et al.
patent: 5387508 (1995-02-01), Jaffe
patent: 5389215 (1995-02-01), Horiuchi et al.
patent: 5437772 (1995-08-01), De Castro et al.
patent: 5494562 (1996-02-01), Maley et al.
patent: 5512489 (1996-04-01), Girault et al.
patent: 5776672 (1998-07-01), Hashimoto et al.
Wang et al. ("Trace Measurements of RNA by Potentiometric Stripping Analysis at Carbon Paste Electrodes", Anal. Chem. 1995, 67, 4065-4070) Nov. 1995.
Wring et al. ("Chemically Modified, Screen-printed Carbon Electrodes*", Analyst, Aug. 1992, vol. 117, p.1281).
CAPLUS abstract of Palecek et al. ("Cyclic voltammetry of nucleic acids and determination of submicrogram quantities of deoxyribonucleic acids by adsorptive stripping voltammetry", anal. Chim. acta (1986), 187, 99-107) Month Unknown.
CAPLUS abstract of Palecek ("New trends in electrochemical analysis of nuceic acids", Bioelectrochem. Bioenerg. (1988), 20(1-30, 179-940 Month Unknown.
Hashimoto et al. ("Sequence-specific Gene Detection with a Gold Electrode Modified with DNA Probes and an Electrochemically Active Dye", Anal. Chem. vol. 66, No. 21, 3830-3833) Month Unknown, 1988.
Green, Monika J., and Paul I. Hilditch, "Disposable Single-Use Sensors," Analytical Proceedings, vol. 28, Nov. 1991, p. 374.
Hall, Jennifer M., James Moore-Smith, Joe V. Bannister & John Higgins, "An Electrochemical Method for Detection of Nucleic Acid Hybridisation," Biochemistry and Molecular Biology International, vol. 32, No. 1, Jan. 1994, pp. 21-27.
Noble, Deborah, "DNA Sequencing on a Chip," Analytical Chemistry, vol. 67, No. 5, Mar. 1, 1995, pp. 201-204.
Ostapczuk, Peter, "Present Potentials and Limitations in the Determination of Trace Elements by Potentiometric Stripping Analysis," Analytica Chimica Acta, 273 (1993), pp. 35-40 Month Unknown.
Palecek, Emil, "Electrochemical Behaviour of Biological Macromolecules," Biochemistry and Bioenergetics, 13 (1988) p. 273 Only First Page Provided Month Unknown.
Rivas, G., and V.M. Solis, "Electrochemical Determination of the Kinetic Parameters of Mushroom Tyrosinase," Biochemistry and Bioenergetics, 29 (1992) pp. 19-28 Month Unknown.
Wang, Joseph, and Baomin Tian, "Mercury-Free Disposable Lead Sensors Based on Potentiometric Stripping Analysis an Gold-Coated Screen Printed Electrodes," unpublished research proposal, Sep., 1995.
Wang, Joseph, Xiaohua Cai, Gustavo Rivas, Haruki Shiraishi, Percio A.M. Farias and Narasaiah Dontha, "DNA Electrochemical Biosensor for the Detection of Short DNA Sequences Related to the Human Immunodeficiency Virus," Analytical Chemistry, vol. 68, No. 15, Aug. 1, 1996, pp. 2629-2634.
Wang, Joseph, Analytical Electrochemistry, Chapter 5, Electro Chemical Sensors, pp. 154-156, VCH Publishers, Inc., New York, 1994. Month Unknown.
Wang, Joseph, Decentralized Electrochemical Monitoring of Trace Metals: From Disposable Strips to Remote Electrodes, Analyst, vol. 119, May 1994, pp. 763-766.
Wang, Joseph, Emanuel Sucman and Baomin Tian, Stripping Potentiometric Measurements of Copper in Blood Using Gold Microelectrodes, Analytica Chemica Acta, 286 (1994) pp. 189-195. Month Unknown.
Wang, Joseph and A. Julio Reviejo, "Organic-Phase Enzyme Electrode for the Determination of Trace Water in Nonaqueous Media," Analytical Chemistry, vol. 65, No. 6, Mar. 15, 1993, pp. 845-847.
Wang, Joseph, and Baomin Tian, "Screen Prined Stripping Voltmmetric/Potentiometric Electrodes for Decentralized Testing of Trace Lead," Analytical Chemistry, vol. 64, No. 15, Aug. 1, 1992, pp. 1706-1709.
Wang, Joseph, "Adsorptive Stripping Votammetry--A New Electroanalytical Avenue for Trace Analysis," Journal of Research on the Nation Bureau of Standards, vol. 91, No. 3, May-Jun. 1988, pp. 489-491.
Wang, Joseph, Stripping Analysis, Chapter 2, Cathode Stripping, pp. 58-60, VCH Publishing, New York, 1985. Month Unknown.
Wangsa, Julie and Mark Arnold, Fiber-Optic Biosensors Based on the Fluorometric Detection of Reduced Nicotinamide Adenine Dinucleotide, Analytical Chemistry, vol. 60, No. 10, May 15, 1988, pp. 1080-1082.
Wring, Stephen and John P. Hart, "Chemically Modified, Screen-Printed Carbon Electrodes," Analyst, vol. 117, Aug. 1992, pp. 1281-1282.
"Oakton.TM. Electrascan" meter for trace levels of heavy metals, manufacture by Cole-Palmer Instrument Company, Chicago, Illinois, product information, Mar. 1991.
Cai Xiaohua
Wang Joseph
Baker Rod D.
Kehl D. Goelet
New Mexico State University Technology Transfer Corporation
Noguerola Alex
Peacock Deborah A.
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