Substituted phenoxyalkanolamines and phenoxyalkanol-cycloalkylam

Details Substituted phenoxyalkanolamines and phenoxyalkanol-cycloalkylam Substituted phenoxyalkanolamines and phenoxyalkanol-cycloalkylam

1986-07-08

1989-09-05

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

26050117, 564347, 564351, 568442, 568586, 568587, C07C 9110, C07C 9306

Patent

active

048640611

ABSTRACT:
New substituted phenoxyalkanolamines and phenoxyalkanol-cycloalkylamines of the general formula I ##STR1## in which R.sup.1 and R.sup.2, which can be identical or different, denote alkyl groups with in each case 1 to 4 carbon atoms, or R.sup.1 and R.sup.2 together denote the group --(CH.sub.2).sub.n --, wherein n is the number 4 or 5, R.sup.3 denotes hydrogen, or an alkyl group or an acyl group with in each case 1 to 6 carbon atoms, R.sub.4 denotes an alkyl group with 1 to 4 carbon atoms or the cyclopropylmethyl group and R.sup.5 denotes hydrogen halogen or alkyl, and acid addition salts thereof, have a cardioselective .beta..sub.1 -adrenolytic and hypotensive action. They can be used as medicaments for the treatment of angina pectoris, hypertension and arrhythmias.

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