Method of treatment for arthritic and inflammatory diseases

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 3144

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active

048639281

ABSTRACT:
A method of treating a human or animal patient suffering from an arthritic disease or associated inflammatory disease comprises daily administration to such patient of from about 1 to about 100 mg of the narcotic antagonists nalmefene or naltrexone. The nalmefene or naltrexone may be administered in equally divided doses from one to four times daily, preferably by the oral route. Parental administration may be utilized where suitable.

REFERENCES:
patent: 4760069 (1988-07-01), Rzeszotarski et al.
Chem. Abst. 107 (1987)-229062x.
Rios et al., Eur. J. Pharm., 96:277-283 (1983).
Kayser et al., Proceedings of the Vth World Congress on Pain, pp. 72-79 (Elsevier Science Publishers 1988).
Hargreaves et al., Proceedings of the Vth World Congress on Pain, pp. 55-60 (Elsevier Science Publishers 1988).

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