Pyridylaminotriazole therapeutic agents

Details Pyridylaminotriazole therapeutic agents Pyridylaminotriazole therapeutic agents

1979-06-18

1981-06-30

Love, Ethel G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546276, 546310, 546324, A61K 3144, C07D40104

Patent

active

042762979

ABSTRACT:
A series of novel 3-amino-5-(4-pyridyl)-1,2,4-triazole derivatives has been prepared, including their pharmaceutically acceptable acid addition salts. These particular compounds are useful in therapy as anti-ulcer agents. Preferred member compounds include 3-amino-5-[2-(N-monomethylamino)-4-pyridyl]-1,2,4-triazole, 3-amino-5-[2-(N-monoethylamino)-4-pyridyl]-1,2,4-triazole and 3-amino-5-[2-(N,N-dimethylamino)-4-pyridyl]-1,2,4-triazole. Alternate methods of preparation are provided and the principal synthetic routes leading to the preferred compounds are described in some detail.

REFERENCES:
patent: 3647814 (1972-03-01), Greenfield
patent: 3663527 (1972-05-01), Schonenbuch
patent: 3813400 (1974-05-01), Boyle et al.
patent: 3873563 (1975-03-01), Kotone et al.
patent: 3879404 (1975-04-01), Baldwin et al.
patent: 4071518 (1978-01-01), Baldwin et al.
patent: 4102889 (1978-07-01), Baldwin et al.
Chem. Abstracts 48:12092 d.
Chem. Abstracts 58:5703 h.
Annual Reports in Medicinal Chem., vol. 14, pp. 91-102, (1979).
Bieman et al., Monatshefte fur Chemie, vol. 89, Nos. 4-5, p. 603, (1958).
Jones et al., Journ. Medicinal Chem., vol. 8, p. 676, (1965).
Yakugaku Zashi, Journ. Pharm. Soc. Japan, vol. 92, No. 4, p. 471, (1972).

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