Amine derivatives and pharmaceutical compositions containing the

Details Amine derivatives and pharmaceutical compositions containing the Amine derivatives and pharmaceutical compositions containing the

1980-06-06

1981-07-21

Raymond, Richard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

548186, 548189, 26032635, 548214, 548336, 26032636, 548337, 548342, 2603264, 549 60, 549 74, 2603265D, 549 75, 549 76, 2603265L, 549 77, 564 27, 26032682, 564 47, 564 56, 26032684, 564 85, 564 86, 26032685, 564104, 564237, 26032686, 564340, 564341, 2603472, 564346, 564353, 2603473, 564356, 564367, 2603477, 424267, 424270, 424272, 424273R, 424275, 424285, 424321, 424322, 424326, 424330, 544242, 544335, 546186, 546194, 546209, 546210, 546213, 546214, 546281, 548146, A61K 3134, A61K 3144, C07D21358, C07D30754

Patent

active

042799112

ABSTRACT:
The invention relates to compounds of the general formula (I) ##STR1## and physiologically acceptable salts, N-oxides, hydrates and bioprecursors thereof, in which Y represents .dbd.O, .dbd.S, .dbd.CHNO.sub.2 or .dbd.NR.sub.3 where R.sub.3 represents hydrogen, nitro, cyano, lower alkyl, aryl, lower alkylsulphonyl or arylsulphonyl; R.sub.1 and R.sub.2, which may be the same or different, each represent hydrogen lower alkyl, cycloalkyl, lower alkenyl, aralkyl, hydroxy, lower trifluoroalkyl, lower alkyl substituted by hydroxy, lower alkoxy, amine, lower alkylamino or dialkylamino, or R.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached form a 5 to 7 membered heterocyclic ring which may contain other heteroatoms or the group ##STR2## where R.sub.4 represents hydrogen or lower alkyl;

REFERENCES:
patent: 4128658 (1978-12-01), Price et al.
patent: 4203909 (1980-05-01), Algieri et al.

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