Purification of sclareolide

Details Purification of sclareolide Purification of sclareolide

1997-03-25

1999-08-31

Dentz, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

435126, C07D30792, C12P 1704

Patent

active

059455462

ABSTRACT:
A method for purifying sclareolide comprises a separation step wherein debris, e.g., microbial cell debris is removed, and further comprises extracting an organic solution of sclareolide with an acid solution, followed by an extraction of the partially purified sclareolide with a basic solution, thus yielding sclareolide of very high purity.

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Ruzicka et. al., "Hohere Terpenverbindungen" etc., Helvetica Chim. Acta, vol. 14, pp. 645-650, 1931.
Sharma et al.; "E.1. A Review on Clary Sage (Salvia Sclarea L.)"; CROMAP, 7(1):39-48 (1985).

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