Cyclic anthranililc acid carboxylic acid derivatives and medical

Details Cyclic anthranililc acid carboxylic acid derivatives and medical Cyclic anthranililc acid carboxylic acid derivatives and medical

1990-06-15

1992-05-12

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546165, C07D21512, A61K 3147

Patent

active

051128365

ABSTRACT:
Cyclic anthranilic acid carboxylic acid derivatives of the following formula, ##STR1## wherein R.sup.1 is hydrogen atom, carboxyl group, lower alkoxy carbonyl group having 1 to 3 carbon atoms, or phenyl group which may be substituted, r.sup.2 and R.sup.4 are each independently a hydrogen atom, lower alkyl group having 1 to 3 carbon atoms or benzyl group, R.sup.3 is a hydrogen atom, halogen atom, nitro group, amino group, cyano group, carbamoyl group, carboxyl group, lower alkanoylamino group having 1 to 4 carbon atoms, benzoylamino group, lower alkylsulfonylamino group having 1 to 3 carbon atoms or phenylsulfonylamino group which may be substituted by methyl group; the acid addition or alkali salts thereof, are useful as drugs treat autoimmune diseases, antirheumatic agents and therapeutic or prophylactic agents to treat metabolic bone diseases.

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