Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1985-12-06
1987-11-24
Lone, Werren B.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
562450, C07C 67313
Patent
active
047090758
ABSTRACT:
Alkyl N-maleylphenylalanate is prepared by reacting the starting material alkyl L-phenylalanate and maleic anhydride in aqueous solution at a pH of at most 7.5. The reaction products can be isomerized with dipolar aprotic solvents into the corresponding fumaric acid monoamides and thus can be used as an intermediate in the preparation of alkyl .alpha.-L-aspartyl-L-phenylalanate.
REFERENCES:
patent: 3901871 (1975-08-01), Anderson
patent: 4507231 (1985-03-01), Gourbault
patent: 4539147 (1985-09-01), Filippini et al.
Clarke Vera C.
Hoechst Aktiengesellschaft
Lone Werren B.
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