Novel dispirodecanes, processes for their preparation and pharma

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...

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2603407, 2603409R, 260338, 260464, 2603265FM, 2603265D, 2603265CA, C07D48710, A61K 3140

Patent

active

040863557

ABSTRACT:
The invention relates to novel spirodecane derivatives and more specifically to novel azaspirodecane diones.
The invention also provides process for producing said azaspirodecane diones which consists mainly in cyclizing a disubstituted glutaronitrile or a glutaric acid in the presence of an amino compound.
The compounds of the present invention have interesting pharmacological properties and they find therapeutical uses.

REFERENCES:
patent: 3238217 (1966-03-01), Grogan et al.
patent: 3534054 (1970-10-01), Porter et al.
patent: 3669986 (1972-06-01), Porter et al.
Jouvet, "Physiological Reviews," vol. 47, #2, pp. 117-142 (1967).
VAN Twyver, Physiology & Behavior, vol. 4, 901-905.

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