Preparation of N-substituted 2-pyrrolidones

Details Preparation of N-substituted 2-pyrrolidones Preparation of N-substituted 2-pyrrolidones

1994-02-04

1995-07-18

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548552, C07D20108, C07D20116

Patent

active

054342732

ABSTRACT:
The preparation of N-substituted 2-pyrrolidones (I) by the reaction of maleic acid, fumaric acid, or succinic acid or functional derivatives of these acids (compounds II) with a primary amine (III) or by the reaction of amides or imides derived from II and III under hydrogenating conditions in a synthesis stage followed by isolation, by distillation, of I and other volatile components from the resulting reaction mixture, in which the residues present following distillation are subjected to further hydrogenation treatment and the compound (I) thus formed is isolated by distillation.

REFERENCES:
patent: 3109005 (1963-10-01), Lidov et al.
patent: 3448118 (1969-06-01), Chichery
patent: 5157127 (1992-10-01), Weyer et al.

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