Process for isolation of cefaclor after enzymatic acylation

Details Process for isolation of cefaclor after enzymatic acylation Process for isolation of cefaclor after enzymatic acylation

Filed on

1993-02-05

Date issued

1995-07-18

Examiner

Rizzo, Nicholas

Patent Class

Organic compounds -- part of the class 532-570 series

SubClass

Organic compounds

SubSubClass

Heterocyclic carbon compounds containing a hetero ring...

Other Related Categories

C07D50112

Type

Patent

Status

active

Patent number

054342597

Description

ABSTRACT:
Provided is a process for isolating cefaclor from an acylation reaction mixture by adding anthraquinone-1,5-disulfonic acid to the mixture. The acid highly selectively precipitates with cefaclor so that isolation and recovery is streamlined.

REFERENCES:
patent: 3676434 (1972-07-01), Massey
patent: 3816253 (1972-03-01), Takahashi et al.
Kang, et al., 7(1987), Purification and Catalytic Properties of Cephalexin Synthesizing Enzyme from Acetobacter turbidans, Kor. J. Appl. Microbiol. Bioeng. 15(3): 203-208.

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