Method for improving brain function using cholinesterase-inhibit

Details Method for improving brain function using cholinesterase-inhibit Method for improving brain function using cholinesterase-inhibit

1994-03-22

1995-07-18

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514655, A61K 3140, A61K 31135

Patent

active

054341795

ABSTRACT:
An aminoketone compound of the formula ##STR1## wherein ring A' means a five through eight-membered cyclic group which may be substituted and may contain one or two hetero atom(s) of O, S, N, as the ring-constituents; R.sup.1' means a hydrogen atom or a hydrocarbon residue which may be substituted; R.sup.2' means a hydrogen atom or a lower alkyl group; R.sup.3' means an aromatic group which may be substituted; R.sup.4' means a hydrogen atom, a lower alkyl group or aromatic group which may be substituted; n' means an integer of 2 to 7, or a salt thereof, is useful as an cholinesterase inhibitors and a cerebral function ameliorating agent.

REFERENCES:
patent: 3197507 (1965-07-01), Freed et al.
patent: 4073797 (1978-02-01), Ramuz
Chemical Abstracts, vol. 72, No. 1, p. 302, item 3333h (1970).
Journal of Medical Chemistry, vol. 32, 1988, pp. 105-108, "Synthesis and Antiallergy Activity of 4-(Diarylhydroxymethyl)-1-[3-(aryloxy)propyl]piperidines and Structurally Related Compounds".
Chemical Abstracts, vol., 64, 1966, p. 8091, Abstract of U.S. Pat. No. 3,197,507.

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