Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-05-28
1995-07-18
Brust, Joseph Paul
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5483014, A61K 31415
Patent
active
054341760
ABSTRACT:
A compound selected from the group consisting of compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of --CN, --NO.sub.2, halogen, --CF.sub.3, free carboxy, salified carboxy, and carboxy esterified with lower alkyl; -A-B- is selected from the group consisting of ##STR2## and X, R.sub.3, R.sub.4 and R.sub.5 are defined as in the specification and their non-toxic, pharmaceutically acceptable acid addition salts having anti-androgenic activity.
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Chemical Abstracts vol. 114, No. 119, Abst. No. 185374 (1991).
Kruger et al., Arch. Pharm 311, pp. 39-47 (1978).
CA. 81, No. 7, Aug. 19, 1984.
Claussner Andre
Goubet Francois
Teutsch Jean-Georges
Brust Joseph Paul
Roussel Uclaf
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