Dopamine-.beta.-hydroxylase inhibitors

Details Dopamine-.beta.-hydroxylase inhibitors Dopamine-.beta.-hydroxylase inhibitors

1989-01-27

1989-08-22

Lee, Mary C.

Package making

548337, C07D23390

Patent

active

048597791

ABSTRACT:
Potent dopamine-.beta.-hydroxylase inhibitors having the formula ##STR1## that are useful to inhibit dopamine-.beta.-hydroxylase activity, pharmaceutical compositions including these inhibitors, and methods of using these inhibitors to inhibit dopamine-.beta.-hydroxylase activity in mammals. Also disclosed are novel intermediates useful in preparing the presently invented inhibitors.

REFERENCES:
patent: 4532331 (1985-07-01), Frazee et al.
patent: 4719223 (1988-01-01), Kaiser et al.

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