Tocopherol-based antiviral agents and method of using same

Details Tocopherol-based antiviral agents and method of using same Tocopherol-based antiviral agents and method of using same

1990-05-08

1992-05-19

Friedman, S. J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514458, A61K 3144, A61K 31355

Patent

active

051149575

ABSTRACT:
This invention relates to methods for inhibiting viral and retroviral replication and for treating viral and retroviral infections via the administration of compositions containing Vitamin E, tocopherol, or a tocopherol derivative and, more particularly, compositions containing .alpha.-tocopherol or a pharmaceutically effective prodrug thereof.

REFERENCES:
Chem. Abst. 111, 167396f (1989).
Machlin, L. J., ed., Handbook of Vitamins, Chapter 3, "Vitamin E", Marcel Dekker, Inc., 1983.
Mukai, et al., J. Org. Chem. 54: 557-560 (1989).
Reimund, E., Medical Hypotheses 23: 39 (1987).
The Merck Index, 10th ed., Merck & Co., Inc., 1983, p. 1437.

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