Suppression of cardiac ventricular fibrillation and cardiac arrh

Details Suppression of cardiac ventricular fibrillation and cardiac arrh Suppression of cardiac ventricular fibrillation and cardiac arrh

1977-03-28

1978-04-25

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

A61K 31205

Patent

active

RE0296180

ABSTRACT:
A method for suppressing cardiac ventricular fibrillation and cardiac arrhythmias in animals, both human and otherwise, by administration of ortho-bromo benzyl ethyldimethylammonium p-toluene-sulfonate (bretylium tosylate). The drug may be administered prophylactically in the prevention of or in the treatment of ventricular fibrillation or cardiac arrhythmias.

REFERENCES:
amer. Drug Index, (1965), pp. 105, 120 & 201.
Merck Manual, 9th Ed., (1956), pp. 202-203.
British Med. Journal, Slomar, 4-1965, pp. 895-896.
New Eng. Journ. Med. Connecticut, Feb. 1965, pp. 277-282.
Phillip E. Leveque, "Anti-Arrhythmie Action of Bretylium", Nature, vol. 207, No. 4993, pp. 203-204, July 10, 1965.

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